RESEARCH

Dr. Dye's area of expertise is developmental cell biology. He studies cells and embryos in attempts to answer fundamental and applied questions in the fields of cell biology, developmental biology, and environmental biology. As such he makes use of cell culture, tissue culture, organ culture and embryo culture. Additionally, his work involves a great deal of microscopy, including bright field, phase contrast, fluorescence, and time-lapse video micrography. The range of organisms used in these studies include slime molds (Dictyostelium discoideum), fish (Oryzias latipes), onions (Allium cepa), frogs (Rana pipiens, Xenopus latipes, Rana sylvatica) and mammals (various strains of mice). Recently, his lab has been looking at cell behavior on artificial extracellular matrices, primary culture of neural and ovarian stem cells, and bioassays of environmental water.

Dr. Dye is Director of the Westside Nature Preserve: www.wcsu.edu/wnp and www.wcsu.edu/wnptoday. Professor Dye has been teaching biology to undergraduates for over forty years and believes that the role of a university professor is to facilitate students' attaining their professional goals; that the faculty, administration, and the very buildings of the campus exist to achieve this end.

WestConn graduates’ biology video honored by life sciences magazine
WestConn 2008 graduates Arjumond Khan and Benjamin Woodhouse have received recognition from the life sciences magazine, The Scientist, for their video capturing the microscopic time-lapse progression of the life cycle of the slime mold species Dictyostelium discoideum. The Scientist 2009 Video Awards, an international competition in which videos were reviewed by judges in the life sciences profession as well as readers of the magazine, cited the video, “Time Lapse Videomicrography of the Life Cycle of Dictyostelium,” as one of three runners-up in the Individual Category division. In his judging notes, Marc Friedmann, chief executive officer of the scientific video-sharing Web site SciVee, praised the work as “a great scientific video short.” Science Channel communicator, science blogger and podcast producer Kirsten Sanford observed in her review, “Time-lapse was a neat effect, and allowed dramatic change to be more apparent.” Khan and Woodhouse conducted their work in videomicography as part of their senior research project at WestConn during the 2007-2008 academic year under the supervision of faculty adviser Dr. Frank Dye, Professor of Biological and Environmental Sciences.

The video recording with microscopic resolution captured three days’ progression in the organism’s life cycle from single-cell myxamoeba feeding on E. coli bacteria to multi-cellular slugs to “fruiting bodies,” called sorocarps, that complete the life cycle by release of spores, which germinate to again produce individual myxamoebae. The finished production compresses the three-day cycle into a 26-second video presentation. Dye noted his former students this year are embarking on the next stage in their academic pursuit of promising careers in the health care field, Khan is a first year student in medical school and Woodhouse is a first year PA (physician’s assistant) student. To view their award-winning video, visit the online presentation at: http://www.scivee.tv/node/11137.

More information on The Scientist Video Awards is available at http://www.the-scientist.com/newsletter/etoc/20090801_sea.html

 

Neurosphere Project; Bioassay Project
Don, Remya, Jessica, Jillian
 

Cell Biology Research Group

Chantal, Fernanda, Juliana, Allane, Erick

 

Selected Publications

Dye, F. J. Dictionary of Developmental Biology and Embryology, Second Edition. Wiley-Blackwell (2012) [more...]

Dye, F. J. Developmental Cell Biology. In, Encyclopedia of Molecular Cell Biology and Molecular Medicine, Meyers, R. A., editor. John Wiley Interscience (2004). [more...]

Dye, F. J. Dictionary of Developmental Biology and Embryology. John Wiley & Sons (2002) [more...]

Ierace, K. & F. Dye Monitoring Stream Water Quality with Mouse Cell Culture and On-Site Allium Tests Bull. Environ. Contam. Toxicol. 66: 470-475 (2001)

Dye, F. J. Human Life Before Birth. Harwood Academic Pub. (2000) [more...]

Dye, F.J. Preparation of Mammalian Meiotic Chromosomes and Spermatozoa/Obtaining Early Mammalian Embryos and Preovulation Oocytes. In, Proceedings of the Workshop/Conferences of the Association for Biology Laboratory Education (ABLE), Glase, J. C., ed. (1997) [more...]


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